SCYL1-FRMD8 Fusion FISH Probe
The SCYL1-FRMD8 Fusion FISH Probe is used to confirm a fusion of the SCYL1 and FRMD8 genes. The fusion of the SCYL1 and FRMD8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCYL1-FRMD8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-RERE | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-REOR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-REGO | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-REGR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-REAQ | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-ORRE | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-OROR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-ORGO | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GORE | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GOOR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GOGO | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GOGR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GRRE | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GROR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GRGO | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GRGR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-AQRE | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-AQOR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-AQGO | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-AQGR | 20 (40 μL) | 200 μL |
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| SCYL1-FRMD8-20-AQAQ | 20 (40 μL) | 200 μL |
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SCYL1 Gene Summary
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: SCY1 Like Pseudokinase 1
Chromosome: CHR11: 65292547 -65306182
Locus: 11q13.1
FRMD8 Gene Summary
The FERM Domain Containing 8 (FRMD8) gene is located on chr11 :65154040-65180995 at 11q13.1.
Gene Name: FERM Domain Containing 8
Chromosome: CHR11: 65154040 -65180995
Locus: 11q13.1
Gene Diseases
The SCYL1 FRMD8 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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