SCRIB-NRBP2 Fusion FISH Probe
The SCRIB-NRBP2 Fusion FISH Probe is used to confirm a fusion of the SCRIB and NRBP2 genes. The fusion of the SCRIB and NRBP2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCRIB-NRBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-RERE | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-REOR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-REGO | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-REGR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-REAQ | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-ORRE | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-OROR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-ORGO | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GORE | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GOOR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GOGO | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GOGR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GRRE | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GROR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GRGO | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GRGR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-AQRE | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-AQOR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-AQGO | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-AQGR | 20 (40 μL) | 200 μL |
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| SCRIB-NRBP2-20-AQAQ | 20 (40 μL) | 200 μL |
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SCRIB Gene Summary
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Scribbled Planar Cell Polarity Protein
Chromosome: CHR8: 144873089 -144897549
Locus: 8q24.3
NRBP2 Gene Summary
The Nuclear Receptor Binding Protein 2 (NRBP2) gene is located on chr8 :144915754-144923146 at 8q24.3.
Gene Name: Nuclear Receptor Binding Protein 2
Chromosome: CHR8: 144915754 -144923146
Locus: 8q24.3
Gene Diseases
The SCRIB NRBP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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