SCO1-ARX Fusion FISH Probe
The SCO1-ARX Fusion FISH Probe is used to confirm a fusion of the SCO1 and ARX genes. The fusion of the SCO1 and ARX genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCO1-ARX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-RERE | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-REOR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-REGO | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-REGR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-REAQ | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-ORRE | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-OROR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-ORGO | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GORE | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GOOR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GOGO | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GOGR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GRRE | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GROR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GRGO | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GRGR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-AQRE | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-AQOR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-AQGO | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-AQGR | 20 (40 μL) | 200 μL |
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| SCO1-ARX-20-AQAQ | 20 (40 μL) | 200 μL |
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SCO1 Gene Summary
Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008]
Gene Name: SCO1, Cytochrome C Oxidase Assembly Protein
Chromosome: CHR17: 10583648 -10600885
Locus: 17p13.1
ARX Gene Summary
This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked cognitive disability and epilepsy. [provided by RefSeq, Jul 2016]
Gene Name: Aristaless Related Homeobox
Chromosome: CHRX: 25021812 -25034065
Locus: Xp21.3
Gene Diseases
The SCO1 ARX Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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