SCNN1A-DCP1B Fusion FISH Probe
The SCNN1A-DCP1B Fusion FISH Probe is used to confirm a fusion of the SCNN1A and DCP1B genes. The fusion of the SCNN1A and DCP1B genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCNN1A-DCP1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-RERE | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-REOR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-REGO | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-REGR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-REAQ | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-ORRE | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-OROR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-ORGO | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GORE | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GOOR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GOGO | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GOGR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GRRE | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GROR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GRGO | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GRGR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-AQRE | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-AQOR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-AQGO | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-AQGR | 20 (40 μL) | 200 μL |
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| SCNN1A-DCP1B-20-AQAQ | 20 (40 μL) | 200 μL |
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SCNN1A Gene Summary
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
Gene Name: Sodium Channel Epithelial 1 Alpha Subunit
Chromosome: CHR12: 6456008 -6486523
Locus: 12p13.31
DCP1B Gene Summary
This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Decapping MRNA 1B
Chromosome: CHR12: 2055213 -2113677
Locus: 12p13.33
Gene Diseases
The SCNN1A DCP1B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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