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SCN8A-ANO2 Fusion FISH Probe

The SCN8A-ANO2 Fusion FISH Probe is used to confirm a fusion of the SCN8A and ANO2 genes. The fusion of the SCN8A and ANO2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SCN8A-ANO2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SCN8A-ANO2-20-RERE 20 (40 μL) 200 μL
SCN8A-ANO2-20-REOR 20 (40 μL) 200 μL
SCN8A-ANO2-20-REGO 20 (40 μL) 200 μL
SCN8A-ANO2-20-REGR 20 (40 μL) 200 μL
SCN8A-ANO2-20-REAQ 20 (40 μL) 200 μL
SCN8A-ANO2-20-ORRE 20 (40 μL) 200 μL
SCN8A-ANO2-20-OROR 20 (40 μL) 200 μL
SCN8A-ANO2-20-ORGO 20 (40 μL) 200 μL
SCN8A-ANO2-20-ORAQ 20 (40 μL) 200 μL
SCN8A-ANO2-20-GORE 20 (40 μL) 200 μL
SCN8A-ANO2-20-GOOR 20 (40 μL) 200 μL
SCN8A-ANO2-20-GOGO 20 (40 μL) 200 μL
SCN8A-ANO2-20-GOGR 20 (40 μL) 200 μL
SCN8A-ANO2-20-GOAQ 20 (40 μL) 200 μL
SCN8A-ANO2-20-GRRE 20 (40 μL) 200 μL
SCN8A-ANO2-20-GROR 20 (40 μL) 200 μL
SCN8A-ANO2-20-GRGO 20 (40 μL) 200 μL
SCN8A-ANO2-20-GRGR 20 (40 μL) 200 μL
SCN8A-ANO2-20-GRAQ 20 (40 μL) 200 μL
SCN8A-ANO2-20-AQRE 20 (40 μL) 200 μL
SCN8A-ANO2-20-AQOR 20 (40 μL) 200 μL
SCN8A-ANO2-20-AQGO 20 (40 μL) 200 μL
SCN8A-ANO2-20-AQGR 20 (40 μL) 200 μL
SCN8A-ANO2-20-AQAQ 20 (40 μL) 200 μL

SCN8A Gene Summary

This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Gene Name: Sodium Voltage-gated Channel Alpha Subunit 8

Chromosome: CHR12: 51985019 -52202299

Locus: 12q13.13

ANO2 Gene Summary

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]

Gene Name: Anoctamin 2

Chromosome: CHR12: 5671816 -6055398

Locus: 12p13.31

Gene Diseases

The SCN8A ANO2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.