SCMH1-CASP9 Fusion FISH Probe
The SCMH1-CASP9 Fusion FISH Probe is used to confirm a fusion of the SCMH1 and CASP9 genes. The fusion of the SCMH1 and CASP9 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCMH1-CASP9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-RERE | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-REOR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-REGO | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-REGR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-REAQ | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-ORRE | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-OROR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-ORGO | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GORE | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GOOR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GOGO | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GOGR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GRRE | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GROR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GRGO | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GRGR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-AQRE | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-AQOR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-AQGO | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-AQGR | 20 (40 μL) | 200 μL |
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| SCMH1-CASP9-20-AQAQ | 20 (40 μL) | 200 μL |
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CASP9 Gene Summary
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: Caspase 9
Chromosome: CHR1: 15818768 -15851285
Locus: 1p36.21
SCMH1 Gene Summary
The Scm Polycomb Group Protein Homolog 1 (SCMH1) gene is located on chr1 :41492870-41707815 at 1p34.2.
Gene Name: Scm Polycomb Group Protein Homolog 1
Chromosome: CHR1: 41492870 -41707815
Locus: 1p34.2
Gene Diseases
The SCMH1 CASP9 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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