SCGB1D2-IQGAP1 Fusion FISH Probe
The SCGB1D2-IQGAP1 Fusion FISH Probe is used to confirm a fusion of the SCGB1D2 and IQGAP1 genes. The fusion of the SCGB1D2 and IQGAP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCGB1D2-IQGAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-RERE | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-REOR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-REGO | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-REGR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-OROR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GORE | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GROR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SCGB1D2-IQGAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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IQGAP1 Gene Summary
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
Gene Name: IQ Motif Containing GTPase Activating Protein 1
Chromosome: CHR15: 90931472 -91045475
Locus: 15q26.1
SCGB1D2 Gene Summary
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]
Gene Name: Secretoglobin Family 1D Member 2
Chromosome: CHR11: 62009723 -62012280
Locus: 11q12.3
Gene Diseases
The SCGB1D2 IQGAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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