SCARB2-NIPSNAP1 Fusion FISH Probe
The SCARB2-NIPSNAP1 Fusion FISH Probe is used to confirm a fusion of the SCARB2 and NIPSNAP1 genes. The fusion of the SCARB2 and NIPSNAP1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCARB2-NIPSNAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-RERE | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-REOR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-REGO | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-REGR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-OROR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GORE | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GROR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SCARB2-NIPSNAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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SCARB2 Gene Summary
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Scavenger Receptor Class B Member 2
Chromosome: CHR4: 77079891 -77135052
Locus: 4q21.1
NIPSNAP1 Gene Summary
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Nipsnap Homolog 1
Chromosome: CHR22: 29950797 -29977326
Locus: 22q12.2
Gene Diseases
The SCARB2 NIPSNAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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