SCAP-SLC25A20 Fusion FISH Probe
The SCAP-SLC25A20 Fusion FISH Probe is used to confirm a fusion of the SCAP and SLC25A20 genes. The fusion of the SCAP and SLC25A20 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCAP-SLC25A20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-RERE | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-REOR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-REGO | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-REGR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-REAQ | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-ORRE | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-OROR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-ORGO | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GORE | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GOOR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GOGO | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GOGR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GRRE | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GROR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GRGO | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GRGR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-AQRE | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-AQOR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-AQGO | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-AQGR | 20 (40 μL) | 200 μL |
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| SCAP-SLC25A20-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A20 Gene Summary
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 25 Member 20
Chromosome: CHR3: 48894355 -48936426
Locus: 3p21.31
SCAP Gene Summary
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: SREBF Chaperone
Chromosome: CHR3: 47455183 -47517445
Locus: 3p21.31
Gene Diseases
The SCAP SLC25A20 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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