SCAMP4-COX8A Fusion FISH Probe
The SCAMP4-COX8A Fusion FISH Probe is used to confirm a fusion of the SCAMP4 and COX8A genes. The fusion of the SCAMP4 and COX8A genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCAMP4-COX8A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-RERE | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-REOR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-REGO | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-REGR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-REAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-ORRE | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-OROR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-ORGO | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GORE | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GOOR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GOGO | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GOGR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GRRE | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GROR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GRGO | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GRGR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-AQRE | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-AQOR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-AQGO | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-AQGR | 20 (40 μL) | 200 μL |
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| SCAMP4-COX8A-20-AQAQ | 20 (40 μL) | 200 μL |
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COX8A Gene Summary
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome C Oxidase Subunit 8A
Chromosome: CHR11: 63742078 -63744015
Locus: 11q13.1
SCAMP4 Gene Summary
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]
Gene Name: Secretory Carrier Membrane Protein 4
Chromosome: CHR19: 1905372 -1926012
Locus: 19p13.3
Gene Diseases
The SCAMP4 COX8A Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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