SCAMP2-PLAUR Fusion FISH Probe
The SCAMP2-PLAUR Fusion FISH Probe is used to confirm a fusion of the SCAMP2 and PLAUR genes. The fusion of the SCAMP2 and PLAUR genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCAMP2-PLAUR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-RERE | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-REOR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-REGO | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-REGR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-REAQ | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-ORRE | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-OROR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-ORGO | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GORE | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GOOR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GOGO | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GOGR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GRRE | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GROR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GRGO | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GRGR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-AQRE | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-AQOR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-AQGO | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-AQGR | 20 (40 μL) | 200 μL |
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| SCAMP2-PLAUR-20-AQAQ | 20 (40 μL) | 200 μL |
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PLAUR Gene Summary
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Gene Name: Plasminogen Activator, Urokinase Receptor
Chromosome: CHR19: 44150246 -44174498
Locus: 19q13.31
SCAMP2 Gene Summary
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Secretory Carrier Membrane Protein 2
Chromosome: CHR15: 75137196 -75165670
Locus: 15q24.1
Gene Diseases
The SCAMP2 PLAUR Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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