SC5DL-SPA17 Fusion FISH Probe
The SC5DL-SPA17 Fusion FISH Probe is used to confirm a fusion of the SC5DL and SPA17 genes. The fusion of the SC5DL and SPA17 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SC5DL-SPA17-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-RERE | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-REOR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-REGO | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-REGR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-REAQ | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-ORRE | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-OROR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-ORGO | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-ORAQ | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GORE | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GOOR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GOGO | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GOGR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GOAQ | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GRRE | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GROR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GRGO | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GRGR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-GRAQ | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-AQRE | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-AQOR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-AQGO | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-AQGR | 20 (40 μL) | 200 μL |
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| SC5DL-SPA17-20-AQAQ | 20 (40 μL) | 200 μL |
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SPA17 Gene Summary
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
Gene Name: Sperm Autoantigenic Protein 17
Chromosome: CHR11: 124543739 -124564687
Locus: 11q24.2
Gene Diseases
The SC5DL SPA17 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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