SBNO2-CACNA2D2 Fusion FISH Probe
The SBNO2-CACNA2D2 Fusion FISH Probe is used to confirm a fusion of the SBNO2 and CACNA2D2 genes. The fusion of the SBNO2 and CACNA2D2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SBNO2-CACNA2D2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-RERE | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-REOR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-REGO | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-REGR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-REAQ | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-ORRE | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-OROR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-ORGO | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GORE | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GOOR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GOGO | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GOGR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GRRE | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GROR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GRGO | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GRGR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-AQRE | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-AQOR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-AQGO | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-AQGR | 20 (40 μL) | 200 μL |
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| SBNO2-CACNA2D2-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNA2D2 Gene Summary
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 2
Chromosome: CHR3: 50400230 -50540892
Locus: 3p21.31
SBNO2 Gene Summary
The Strawberry Notch Homolog 2 (SBNO2) gene is located on chr19 :1107632-1174282 at 19p13.3.
Gene Name: Strawberry Notch Homolog 2
Chromosome: CHR19: 1107632 -1174282
Locus: 19p13.3
Gene Diseases
The SBNO2 CACNA2D2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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