SBF2-PRMT3 Fusion FISH Probe
The SBF2-PRMT3 Fusion FISH Probe is used to confirm a fusion of the SBF2 and PRMT3 genes. The fusion of the SBF2 and PRMT3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SBF2-PRMT3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-RERE | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-REOR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-REGO | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-REGR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-REAQ | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-ORRE | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-OROR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-ORGO | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-ORAQ | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GORE | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GOOR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GOGO | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GOGR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GOAQ | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GRRE | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GROR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GRGO | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GRGR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-GRAQ | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-AQRE | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-AQOR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-AQGO | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-AQGR | 20 (40 μL) | 200 μL |
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| SBF2-PRMT3-20-AQAQ | 20 (40 μL) | 200 μL |
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PRMT3 Gene Summary
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Protein Arginine Methyltransferase 3
Chromosome: CHR11: 20409075 -20530879
Locus: 11p15.1
SBF2 Gene Summary
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
Gene Name: SET Binding Factor 2
Chromosome: CHR11: 9800213 -10315754
Locus: 11p15.4
Gene Diseases
The SBF2 PRMT3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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