SAT1-CTTN Fusion FISH Probe
The SAT1-CTTN Fusion FISH Probe is used to confirm a fusion of the SAT1 and CTTN genes. The fusion of the SAT1 and CTTN genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAT1-CTTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-RERE | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-REOR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-REGO | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-REGR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-REAQ | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-ORRE | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-OROR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-ORGO | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GORE | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GOOR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GOGO | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GOGR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GRRE | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GROR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GRGO | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GRGR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-AQRE | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-AQOR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-AQGO | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-AQGR | 20 (40 μL) | 200 μL |
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| SAT1-CTTN-20-AQAQ | 20 (40 μL) | 200 μL |
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CTTN Gene Summary
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Gene Name: Cortactin
Chromosome: CHR11: 70244611 -70282690
Locus: 11q13.3
SAT1 Gene Summary
The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Spermidine/spermine N1-acetyltransferase 1
Chromosome: CHRX: 23801274 -23804327
Locus: Xp22.11
Gene Diseases
The SAT1 CTTN Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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