SASH1-STAB2 Fusion FISH Probe
The SASH1-STAB2 Fusion FISH Probe is used to confirm a fusion of the SASH1 and STAB2 genes. The fusion of the SASH1 and STAB2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SASH1-STAB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SASH1-STAB2-20-AQAQ | 20 (40 μL) | 200 μL |
|
SASH1 Gene Summary
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]
Gene Name: SAM And SH3 Domain Containing 1
Chromosome: CHR6: 148663728 -148873184
Locus: 6q24.3-q25.1
STAB2 Gene Summary
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
Gene Name: Stabilin 2
Chromosome: CHR12: 103981068 -104160502
Locus: 12q23.3
Gene Diseases
The SASH1 STAB2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|