SART3-DAO Fusion FISH Probe
The SART3-DAO Fusion FISH Probe is used to confirm a fusion of the SART3 and DAO genes. The fusion of the SART3 and DAO genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SART3-DAO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-RERE | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-REOR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-REGO | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-REGR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-REAQ | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-ORRE | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-OROR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-ORGO | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-ORAQ | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GORE | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GOOR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GOGO | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GOGR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GOAQ | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GRRE | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GROR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GRGO | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GRGR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-GRAQ | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-AQRE | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-AQOR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-AQGO | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-AQGR | 20 (40 μL) | 200 μL |
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| SART3-DAO-20-AQAQ | 20 (40 μL) | 200 μL |
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DAO Gene Summary
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
Gene Name: D-amino Acid Oxidase
Chromosome: CHR12: 109273856 -109294710
Locus: 12q24.11
SART3 Gene Summary
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Name: Squamous Cell Carcinoma Antigen Recognized By T-cells 3
Chromosome: CHR12: 108915990 -108955165
Locus: 12q23.3
Gene Diseases
The SART3 DAO Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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