SART3-CORO1C Fusion FISH Probe
The SART3-CORO1C Fusion FISH Probe is used to confirm a fusion of the SART3 and CORO1C genes. The fusion of the SART3 and CORO1C genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SART3-CORO1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-RERE | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-REOR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-REGO | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-REGR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-REAQ | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-ORRE | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-OROR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-ORGO | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GORE | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GOOR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GOGO | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GOGR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GRRE | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GROR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GRGO | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GRGR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-AQRE | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-AQOR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-AQGO | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-AQGR | 20 (40 μL) | 200 μL |
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| SART3-CORO1C-20-AQAQ | 20 (40 μL) | 200 μL |
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SART3 Gene Summary
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Name: Squamous Cell Carcinoma Antigen Recognized By T-cells 3
Chromosome: CHR12: 108915990 -108955165
Locus: 12q23.3
CORO1C Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Coronin 1C
Chromosome: CHR12: 109038886 -109125295
Locus: 12q24.11
Gene Diseases
The SART3 CORO1C Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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