SAMD4A-LRBA Fusion FISH Probe
The SAMD4A-LRBA Fusion FISH Probe is used to confirm a fusion of the SAMD4A and LRBA genes. The fusion of the SAMD4A and LRBA genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAMD4A-LRBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-RERE | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-REOR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-REGO | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-REGR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-REAQ | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-ORRE | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-OROR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-ORGO | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GORE | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GOOR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GOGO | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GROR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GRGO | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GRGR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-AQRE | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-AQOR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-AQGO | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-AQGR | 20 (40 μL) | 200 μL |
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| SAMD4A-LRBA-20-AQAQ | 20 (40 μL) | 200 μL |
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LRBA Gene Summary
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: LPS Responsive Beige-like Anchor Protein
Chromosome: CHR4: 151185810 -151936649
Locus: 4q31.3
SAMD4A Gene Summary
Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]
Gene Name: Sterile Alpha Motif Domain Containing 4A
Chromosome: CHR14: 55034329 -55260033
Locus: 14q22.2
Gene Diseases
The SAMD4A LRBA Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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