SAE1-ZBTB45 Fusion FISH Probe
The SAE1-ZBTB45 Fusion FISH Probe is used to confirm a fusion of the SAE1 and ZBTB45 genes. The fusion of the SAE1 and ZBTB45 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAE1-ZBTB45-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-RERE | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-REOR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-REGO | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-REGR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-REAQ | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-ORRE | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-OROR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-ORGO | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GORE | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GOOR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GOGO | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GOGR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GRRE | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GROR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GRGO | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GRGR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-AQRE | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-AQOR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-AQGO | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-AQGR | 20 (40 μL) | 200 μL |
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| SAE1-ZBTB45-20-AQAQ | 20 (40 μL) | 200 μL |
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SAE1 Gene Summary
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Gene Name: SUMO1 Activating Enzyme Subunit 1
Chromosome: CHR19: 47634079 -47713893
Locus: 19q13.32
ZBTB45 Gene Summary
The Zinc Finger And BTB Domain Containing 45 (ZBTB45) gene is located on chr19 :59024896-59030921 at 19q13.43.
Gene Name: Zinc Finger And BTB Domain Containing 45
Chromosome: CHR19: 59024896 -59030921
Locus: 19q13.43
Gene Diseases
The SAE1 ZBTB45 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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