SAC3D1-SNX15 Fusion FISH Probe
The SAC3D1-SNX15 Fusion FISH Probe is used to confirm a fusion of the SAC3D1 and SNX15 genes. The fusion of the SAC3D1 and SNX15 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAC3D1-SNX15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-RERE | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-REOR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-REGO | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-REGR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-REAQ | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-ORRE | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-OROR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-ORGO | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GORE | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GOOR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GOGO | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GOGR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GRRE | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GROR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GRGO | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GRGR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-AQRE | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-AQOR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-AQGO | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-AQGR | 20 (40 μL) | 200 μL |
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| SAC3D1-SNX15-20-AQAQ | 20 (40 μL) | 200 μL |
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SAC3D1 Gene Summary
The SAC3 Domain Containing 1 (SAC3D1) gene is located on chr11 :64808375-64812300 at 11q13.1.
Gene Name: SAC3 Domain Containing 1
Chromosome: CHR11: 64808375 -64812300
Locus: 11q13.1
SNX15 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
Gene Name: Sorting Nexin 15
Chromosome: CHR11: 64794879 -64808044
Locus: 11q13.1
Gene Diseases
The SAC3D1 SNX15 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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