S100A9-NDUFV1 Fusion FISH Probe
The S100A9-NDUFV1 Fusion FISH Probe is used to confirm a fusion of the S100A9 and NDUFV1 genes. The fusion of the S100A9 and NDUFV1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A9-NDUFV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-RERE | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-REOR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-REGO | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-REGR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-OROR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GORE | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GROR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A9-NDUFV1-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFV1 Gene Summary
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit V1
Chromosome: CHR11: 67374322 -67380012
Locus: 11q13.2
S100A9 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014]
Gene Name: S100 Calcium Binding Protein A9
Chromosome: CHR1: 153330329 -153333503
Locus: 1q21.3
Gene Diseases
The S100A9 NDUFV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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