S100A6-PLEKHB2 Fusion FISH Probe
The S100A6-PLEKHB2 Fusion FISH Probe is used to confirm a fusion of the S100A6 and PLEKHB2 genes. The fusion of the S100A6 and PLEKHB2 genes has been associated with Lung Squamous Cell Carcinoma, Thyroid Carcinoma, and Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A6-PLEKHB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-RERE | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-REOR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-REGO | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-REGR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-OROR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GORE | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GROR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A6-PLEKHB2-20-AQAQ | 20 (40 μL) | 200 μL |
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S100A6 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A6
Chromosome: CHR1: 153507075 -153508717
Locus: 1q21.3
PLEKHB2 Gene Summary
The Pleckstrin Homology Domain Containing B2 (PLEKHB2) gene is located on chr2 :131862419-131907425 at 2q21.1.
Gene Name: Pleckstrin Homology Domain Containing B2
Chromosome: CHR2: 131862419 -131907425
Locus: 2q21.1
Gene Diseases
The S100A6 PLEKHB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Thyroid Carcinoma |
| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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