S100A6-DDX27 Fusion FISH Probe
The S100A6-DDX27 Fusion FISH Probe is used to confirm a fusion of the S100A6 and DDX27 genes. The fusion of the S100A6 and DDX27 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A6-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A6-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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S100A6 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A6
Chromosome: CHR1: 153507075 -153508717
Locus: 1q21.3
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The S100A6 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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