S100A6-COL6A1 Fusion FISH Probe
The S100A6-COL6A1 Fusion FISH Probe is used to confirm a fusion of the S100A6 and COL6A1 genes. The fusion of the S100A6 and COL6A1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A6-COL6A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-RERE | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-REOR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-REGO | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-REGR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-OROR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GORE | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GROR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A6-COL6A1-20-AQAQ | 20 (40 μL) | 200 μL |
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COL6A1 Gene Summary
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type VI Alpha 1 Chain
Chromosome: CHR21: 47401662 -47424963
Locus: 21q22.3
S100A6 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A6
Chromosome: CHR1: 153507075 -153508717
Locus: 1q21.3
Gene Diseases
The S100A6 COL6A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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