S100A2-FXYD3 Fusion FISH Probe
The S100A2-FXYD3 Fusion FISH Probe is used to confirm a fusion of the S100A2 and FXYD3 genes. The fusion of the S100A2 and FXYD3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A2-FXYD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-RERE | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-REOR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-REGO | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-REGR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-OROR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GORE | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GROR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A2-FXYD3-20-AQAQ | 20 (40 μL) | 200 μL |
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FXYD3 Gene Summary
This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Gene Name: FXYD Domain Containing Ion Transport Regulator 3
Chromosome: CHR19: 35606731 -35615228
Locus: 19q13.12
S100A2 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A2
Chromosome: CHR1: 153533584 -153538306
Locus: 1q21.3
Gene Diseases
The S100A2 FXYD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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