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S100A2-DDX21 Fusion FISH Probe

The S100A2-DDX21 Fusion FISH Probe is used to confirm a fusion of the S100A2 and DDX21 genes. The fusion of the S100A2 and DDX21 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
S100A2-DDX21-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
S100A2-DDX21-20-RERE 20 (40 μL) 200 μL
S100A2-DDX21-20-REOR 20 (40 μL) 200 μL
S100A2-DDX21-20-REGO 20 (40 μL) 200 μL
S100A2-DDX21-20-REGR 20 (40 μL) 200 μL
S100A2-DDX21-20-REAQ 20 (40 μL) 200 μL
S100A2-DDX21-20-ORRE 20 (40 μL) 200 μL
S100A2-DDX21-20-OROR 20 (40 μL) 200 μL
S100A2-DDX21-20-ORGO 20 (40 μL) 200 μL
S100A2-DDX21-20-ORAQ 20 (40 μL) 200 μL
S100A2-DDX21-20-GORE 20 (40 μL) 200 μL
S100A2-DDX21-20-GOOR 20 (40 μL) 200 μL
S100A2-DDX21-20-GOGO 20 (40 μL) 200 μL
S100A2-DDX21-20-GOGR 20 (40 μL) 200 μL
S100A2-DDX21-20-GOAQ 20 (40 μL) 200 μL
S100A2-DDX21-20-GRRE 20 (40 μL) 200 μL
S100A2-DDX21-20-GROR 20 (40 μL) 200 μL
S100A2-DDX21-20-GRGO 20 (40 μL) 200 μL
S100A2-DDX21-20-GRGR 20 (40 μL) 200 μL
S100A2-DDX21-20-GRAQ 20 (40 μL) 200 μL
S100A2-DDX21-20-AQRE 20 (40 μL) 200 μL
S100A2-DDX21-20-AQOR 20 (40 μL) 200 μL
S100A2-DDX21-20-AQGO 20 (40 μL) 200 μL
S100A2-DDX21-20-AQGR 20 (40 μL) 200 μL
S100A2-DDX21-20-AQAQ 20 (40 μL) 200 μL

S100A2 Gene Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008]

Gene Name: S100 Calcium Binding Protein A2

Chromosome: CHR1: 153533584 -153538306

Locus: 1q21.3

DDX21 Gene Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]

Gene Name: DExD-box Helicase 21

Chromosome: CHR10: 70715891 -70744279

Locus: 10q22.1

Gene Diseases

The S100A2 DDX21 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.