S100A13-GBA Fusion FISH Probe
The S100A13-GBA Fusion FISH Probe is used to confirm a fusion of the S100A13 and GBA genes. The fusion of the S100A13 and GBA genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A13-GBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-RERE | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-REOR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-REGO | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-REGR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-OROR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GORE | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GROR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A13-GBA-20-AQAQ | 20 (40 μL) | 200 μL |
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GBA Gene Summary
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Gene Name: Glucosylceramidase Beta
Chromosome: CHR1: 155204238 -155214653
Locus: 1q22
S100A13 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A13
Chromosome: CHR1: 153591275 -153606568
Locus: 1q21.3
Gene Diseases
The S100A13 GBA Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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