RXRA-WDR5 Fusion FISH Probe
The RXRA-WDR5 Fusion FISH Probe is used to confirm a fusion of the RXRA and WDR5 genes. The fusion of the RXRA and WDR5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RXRA-WDR5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-RERE | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-REOR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-REGO | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-REGR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-REAQ | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-ORRE | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-OROR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-ORGO | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-ORAQ | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GORE | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GOOR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GOGO | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GOGR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GOAQ | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GRRE | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GROR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GRGO | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GRGR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-GRAQ | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-AQRE | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-AQOR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-AQGO | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-AQGR | 20 (40 μL) | 200 μL |
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| RXRA-WDR5-20-AQAQ | 20 (40 μL) | 200 μL |
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RXRA Gene Summary
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Retinoid X Receptor Alpha
Chromosome: CHR9: 137218315 -137332431
Locus: 9q34.2
WDR5 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 5
Chromosome: CHR9: 137001209 -137025094
Locus: 9q34.2
Gene Diseases
The RXRA WDR5 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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