RTKN-CTF1 Fusion FISH Probe
The RTKN-CTF1 Fusion FISH Probe is used to confirm a fusion of the RTKN and CTF1 genes. The fusion of the RTKN and CTF1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RTKN-CTF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-RERE | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-REOR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-REGO | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-REGR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-REAQ | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-ORRE | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-OROR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-ORGO | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GORE | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GOOR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GOGO | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GOGR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GRRE | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GROR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GRGO | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GRGR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-AQRE | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-AQOR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-AQGO | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-AQGR | 20 (40 μL) | 200 μL |
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| RTKN-CTF1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTF1 Gene Summary
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Cardiotrophin 1
Chromosome: CHR16: 30907927 -30914881
Locus: 16p11.2
RTKN Gene Summary
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Rhotekin
Chromosome: CHR2: 74652987 -74669060
Locus: 2p13.1
Gene Diseases
The RTKN CTF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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