RSF1-KLC2 Fusion FISH Probe
The RSF1-KLC2 Fusion FISH Probe is used to confirm a fusion of the RSF1 and KLC2 genes. The fusion of the RSF1 and KLC2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RSF1-KLC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-RERE | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-REOR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-REGO | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-REGR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-REAQ | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-ORRE | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-OROR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-ORGO | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GORE | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GOOR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GOGO | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GOGR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GRRE | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GROR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GRGO | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GRGR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-AQRE | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-AQOR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-AQGO | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-AQGR | 20 (40 μL) | 200 μL |
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| RSF1-KLC2-20-AQAQ | 20 (40 μL) | 200 μL |
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RSF1 Gene Summary
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]
Gene Name: Remodeling And Spacing Factor 1
Chromosome: CHR11: 77377273 -77531880
Locus: 11q14.1
KLC2 Gene Summary
The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016]
Gene Name: Kinesin Light Chain 2
Chromosome: CHR11: 66024764 -66035331
Locus: 11q13.2
Gene Diseases
The RSF1 KLC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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