RSF1-INTS4 Fusion FISH Probe
The RSF1-INTS4 Fusion FISH Probe is used to confirm a fusion of the RSF1 and INTS4 genes. The fusion of the RSF1 and INTS4 genes has been associated with Lung Squamous Cell Carcinoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RSF1-INTS4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-RERE | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-REOR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-REGO | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-REGR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-REAQ | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-ORRE | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-OROR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-ORGO | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-ORAQ | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GORE | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GOOR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GOGO | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GOGR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GOAQ | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GRRE | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GROR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GRGO | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GRGR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-GRAQ | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-AQRE | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-AQOR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-AQGO | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-AQGR | 20 (40 μL) | 200 μL |
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| RSF1-INTS4-20-AQAQ | 20 (40 μL) | 200 μL |
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RSF1 Gene Summary
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]
Gene Name: Remodeling And Spacing Factor 1
Chromosome: CHR11: 77377273 -77531880
Locus: 11q14.1
INTS4 Gene Summary
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Name: Integrator Complex Subunit 4
Chromosome: CHR11: 77589765 -77705717
Locus: 11q14.1
Gene Diseases
The RSF1 INTS4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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