RSF1-ADAM2 Fusion FISH Probe
The RSF1-ADAM2 Fusion FISH Probe is used to confirm a fusion of the RSF1 and ADAM2 genes. The fusion of the RSF1 and ADAM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RSF1-ADAM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-RERE | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-REOR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-REGO | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-REGR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-REAQ | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-ORRE | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-OROR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-ORGO | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GORE | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GOOR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GOGO | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GOGR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GRRE | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GROR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GRGO | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GRGR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-AQRE | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-AQOR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-AQGO | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-AQGR | 20 (40 μL) | 200 μL |
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| RSF1-ADAM2-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAM2 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Name: ADAM Metallopeptidase Domain 2
Chromosome: CHR8: 39601254 -39695779
Locus: 8p11.22
RSF1 Gene Summary
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]
Gene Name: Remodeling And Spacing Factor 1
Chromosome: CHR11: 77377273 -77531880
Locus: 11q14.1
Gene Diseases
The RSF1 ADAM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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