RSBN1L-HGF Fusion FISH Probe
The RSBN1L-HGF Fusion FISH Probe is used to confirm a fusion of the RSBN1L and HGF genes. The fusion of the RSBN1L and HGF genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RSBN1L-HGF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-RERE | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-REOR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-REGO | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-REGR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-REAQ | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-ORRE | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-OROR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-ORGO | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-ORAQ | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GORE | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GOOR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GOGO | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GOGR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GOAQ | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GRRE | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GROR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GRGO | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GRGR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-GRAQ | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-AQRE | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-AQOR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-AQGO | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-AQGR | 20 (40 μL) | 200 μL |
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| RSBN1L-HGF-20-AQAQ | 20 (40 μL) | 200 μL |
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HGF Gene Summary
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
Gene Name: Hepatocyte Growth Factor
Chromosome: CHR7: 81331443 -81399452
Locus: 7q21.11
RSBN1L Gene Summary
The Round Spermatid Basic Protein 1 Like (RSBN1L) gene is located on chr7 :77325742-77409120 at 7q11.23.
Gene Name: Round Spermatid Basic Protein 1 Like
Chromosome: CHR7: 77325742 -77409120
Locus: 7q11.23
Gene Diseases
The RSBN1L HGF Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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