RRP12-EXOSC1 Fusion FISH Probe
The RRP12-EXOSC1 Fusion FISH Probe is used to confirm a fusion of the RRP12 and EXOSC1 genes. The fusion of the RRP12 and EXOSC1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RRP12-EXOSC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RRP12-EXOSC1-20-AQAQ | 20 (40 μL) | 200 μL |
|
RRP12 Gene Summary
The Ribosomal RNA Processing 12 Homolog (RRP12) gene is located on chr10 :99116457-99161127 at 10q24.1.
Gene Name: Ribosomal RNA Processing 12 Homolog
Chromosome: CHR10: 99116457 -99161127
Locus: 10q24.1
EXOSC1 Gene Summary
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Exosome Component 1
Chromosome: CHR10: 99195665 -99205768
Locus: 10q24.1
Gene Diseases
The RRP12 EXOSC1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|