RRM2B-ZNF704 Fusion FISH Probe
The RRM2B-ZNF704 Fusion FISH Probe is used to confirm a fusion of the RRM2B and ZNF704 genes. The fusion of the RRM2B and ZNF704 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RRM2B-ZNF704-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-RERE | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-REOR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-REGO | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-REGR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-REAQ | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-ORRE | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-OROR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-ORGO | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-ORAQ | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GORE | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GOOR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GOGO | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GOGR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GOAQ | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GRRE | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GROR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GRGO | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GRGR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-GRAQ | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-AQRE | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-AQOR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-AQGO | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-AQGR | 20 (40 μL) | 200 μL |
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| RRM2B-ZNF704-20-AQAQ | 20 (40 μL) | 200 μL |
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RRM2B Gene Summary
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Gene Name: Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B
Chromosome: CHR8: 103216728 -103251346
Locus: 8q22.3
ZNF704 Gene Summary
The Zinc Finger Protein 704 (ZNF704) gene is located on chr8 :81540685-81787016 at 8q21.13.
Gene Name: Zinc Finger Protein 704
Chromosome: CHR8: 81540685 -81787016
Locus: 8q21.13
Gene Diseases
The RRM2B ZNF704 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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