RREB1-EEF1E1 Fusion FISH Probe
The RREB1-EEF1E1 Fusion FISH Probe is used to confirm a fusion of the RREB1 and EEF1E1 genes. The fusion of the RREB1 and EEF1E1 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RREB1-EEF1E1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-RERE | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-REOR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-REGO | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-REGR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-REAQ | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-ORRE | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-OROR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-ORGO | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GORE | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GOOR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GOGO | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GOGR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GRRE | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GROR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GRGO | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GRGR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-AQRE | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-AQOR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-AQGO | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-AQGR | 20 (40 μL) | 200 μL |
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| RREB1-EEF1E1-20-AQAQ | 20 (40 μL) | 200 μL |
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RREB1 Gene Summary
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Name: Ras Responsive Element Binding Protein 1
Chromosome: CHR6: 7107829 -7252213
Locus: 6p24.3
EEF1E1 Gene Summary
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
Gene Name: Eukaryotic Translation Elongation Factor 1 Epsilon 1
Chromosome: CHR6: 8073592 -8102828
Locus: 6p24.3
Gene Diseases
The RREB1 EEF1E1 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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