RRAS2-PSMA1 Fusion FISH Probe
The RRAS2-PSMA1 Fusion FISH Probe is used to confirm a fusion of the RRAS2 and PSMA1 genes. The fusion of the RRAS2 and PSMA1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RRAS2-PSMA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-RERE | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-REOR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-REGO | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-REGR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-REAQ | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-ORRE | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-OROR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-ORGO | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GORE | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GOOR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GOGO | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GOGR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GRRE | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GROR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GRGO | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GRGR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-AQRE | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-AQOR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-AQGO | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-AQGR | 20 (40 μL) | 200 μL |
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| RRAS2-PSMA1-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMA1 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Gene Name: Proteasome Subunit Alpha 1
Chromosome: CHR11: 14526421 -14665180
Locus: 11p15.2
RRAS2 Gene Summary
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Name: RAS Related 2
Chromosome: CHR11: 14299465 -14386052
Locus: 11p15.2
Gene Diseases
The RRAS2 PSMA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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