RRAGC-RHBDL2 Fusion FISH Probe
The RRAGC-RHBDL2 Fusion FISH Probe is used to confirm a fusion of the RRAGC and RHBDL2 genes. The fusion of the RRAGC and RHBDL2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RRAGC-RHBDL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-RERE | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-REOR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-REGO | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-REGR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-REAQ | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-ORRE | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-OROR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-ORGO | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GORE | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GOOR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GOGO | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GOGR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GRRE | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GROR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GRGO | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GRGR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-AQRE | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-AQOR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-AQGO | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-AQGR | 20 (40 μL) | 200 μL |
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| RRAGC-RHBDL2-20-AQAQ | 20 (40 μL) | 200 μL |
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RHBDL2 Gene Summary
The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
Gene Name: Rhomboid Like 2
Chromosome: CHR1: 39351478 -39407456
Locus: 1p34.3
RRAGC Gene Summary
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Name: Ras Related GTP Binding C
Chromosome: CHR1: 39305014 -39325340
Locus: 1p34.3
Gene Diseases
The RRAGC RHBDL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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