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RPTOR-TMEM105 Fusion FISH Probe

The RPTOR-TMEM105 Fusion FISH Probe is used to confirm a fusion of the RPTOR and TMEM105 genes. The fusion of the RPTOR and TMEM105 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RPTOR-TMEM105-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RPTOR-TMEM105-20-RERE 20 (40 μL) 200 μL
RPTOR-TMEM105-20-REOR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-REGO 20 (40 μL) 200 μL
RPTOR-TMEM105-20-REGR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-REAQ 20 (40 μL) 200 μL
RPTOR-TMEM105-20-ORRE 20 (40 μL) 200 μL
RPTOR-TMEM105-20-OROR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-ORGO 20 (40 μL) 200 μL
RPTOR-TMEM105-20-ORAQ 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GORE 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GOOR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GOGO 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GOGR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GOAQ 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GRRE 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GROR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GRGO 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GRGR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-GRAQ 20 (40 μL) 200 μL
RPTOR-TMEM105-20-AQRE 20 (40 μL) 200 μL
RPTOR-TMEM105-20-AQOR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-AQGO 20 (40 μL) 200 μL
RPTOR-TMEM105-20-AQGR 20 (40 μL) 200 μL
RPTOR-TMEM105-20-AQAQ 20 (40 μL) 200 μL

RPTOR Gene Summary

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Gene Name: Regulatory Associated Protein Of MTOR Complex 1

Chromosome: CHR17: 78518624 -78940173

Locus: 17q25.3

TMEM105 Gene Summary

The Transmembrane Protein 105 (TMEM105) gene is located on chr17 :79285071-79304474 at 17q25.3.

Gene Name: Transmembrane Protein 105

Chromosome: CHR17: 79285071 -79304474

Locus: 17q25.3

Gene Diseases

The RPTOR TMEM105 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.