RPTOR-TMEM105 Fusion FISH Probe
The RPTOR-TMEM105 Fusion FISH Probe is used to confirm a fusion of the RPTOR and TMEM105 genes. The fusion of the RPTOR and TMEM105 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPTOR-TMEM105-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-RERE | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-REOR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-REGO | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-REGR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-REAQ | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-ORRE | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-OROR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-ORGO | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GORE | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GOOR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GOGO | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GOGR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GRRE | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GROR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GRGO | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GRGR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-AQRE | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-AQOR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-AQGO | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-AQGR | 20 (40 μL) | 200 μL |
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| RPTOR-TMEM105-20-AQAQ | 20 (40 μL) | 200 μL |
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RPTOR Gene Summary
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Regulatory Associated Protein Of MTOR Complex 1
Chromosome: CHR17: 78518624 -78940173
Locus: 17q25.3
TMEM105 Gene Summary
The Transmembrane Protein 105 (TMEM105) gene is located on chr17 :79285071-79304474 at 17q25.3.
Gene Name: Transmembrane Protein 105
Chromosome: CHR17: 79285071 -79304474
Locus: 17q25.3
Gene Diseases
The RPTOR TMEM105 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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