RPTOR-CD163 Fusion FISH Probe
The RPTOR-CD163 Fusion FISH Probe is used to confirm a fusion of the RPTOR and CD163 genes. The fusion of the RPTOR and CD163 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPTOR-CD163-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-RERE | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-REOR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-REGO | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-REGR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-REAQ | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-ORRE | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-OROR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-ORGO | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GORE | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GOOR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GOGO | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GOGR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GRRE | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GROR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GRGO | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GRGR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-AQRE | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-AQOR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-AQGO | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-AQGR | 20 (40 μL) | 200 μL |
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| RPTOR-CD163-20-AQAQ | 20 (40 μL) | 200 μL |
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CD163 Gene Summary
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: CD163 Molecule
Chromosome: CHR12: 7623411 -7656414
Locus: 12p13.31
RPTOR Gene Summary
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Regulatory Associated Protein Of MTOR Complex 1
Chromosome: CHR17: 78518624 -78940173
Locus: 17q25.3
Gene Diseases
The RPTOR CD163 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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