RPS6KC1-TFPI Fusion FISH Probe
The RPS6KC1-TFPI Fusion FISH Probe is used to confirm a fusion of the RPS6KC1 and TFPI genes. The fusion of the RPS6KC1 and TFPI genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS6KC1-TFPI-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-RERE | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-REOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-REGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-REGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-OROR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GORE | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GROR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-TFPI-20-AQAQ | 20 (40 μL) | 200 μL |
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TFPI Gene Summary
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Gene Name: Tissue Factor Pathway Inhibitor
Chromosome: CHR2: 188328957 -188419219
Locus: 2q32.1
RPS6KC1 Gene Summary
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
Gene Name: Ribosomal Protein S6 Kinase C1
Chromosome: CHR1: 213224587 -213446808
Locus: 1q32.3
Gene Diseases
The RPS6KC1 TFPI Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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