RPS6KC1-LYST Fusion FISH Probe
The RPS6KC1-LYST Fusion FISH Probe is used to confirm a fusion of the RPS6KC1 and LYST genes. The fusion of the RPS6KC1 and LYST genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS6KC1-LYST-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-RERE | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-REOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-REGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-REGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-OROR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GORE | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GROR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS6KC1-LYST-20-AQAQ | 20 (40 μL) | 200 μL |
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LYST Gene Summary
This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013]
Gene Name: Lysosomal Trafficking Regulator
Chromosome: CHR1: 235824344 -236030220
Locus: 1q42.3
RPS6KC1 Gene Summary
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
Gene Name: Ribosomal Protein S6 Kinase C1
Chromosome: CHR1: 213224587 -213446808
Locus: 1q32.3
Gene Diseases
The RPS6KC1 LYST Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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