RPS6KA5-BMP4 Fusion FISH Probe
The RPS6KA5-BMP4 Fusion FISH Probe is used to confirm a fusion of the RPS6KA5 and BMP4 genes. The fusion of the RPS6KA5 and BMP4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPS6KA5-BMP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RPS6KA5-BMP4-20-AQAQ | 20 (40 μL) | 200 μL |
|
BMP4 Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Gene Name: Bone Morphogenetic Protein 4
Chromosome: CHR14: 54416454 -54423554
Locus: 14q22.2
RPS6KA5 Gene Summary
The Ribosomal Protein S6 Kinase A5 (RPS6KA5) gene is located on chr14 :91337166-91526993 at 14q32.11.
Gene Name: Ribosomal Protein S6 Kinase A5
Chromosome: CHR14: 91337166 -91526993
Locus: 14q32.11
Gene Diseases
The RPS6KA5 BMP4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|