RPS6KA4-CCDC88B Fusion FISH Probe
The RPS6KA4-CCDC88B Fusion FISH Probe is used to confirm a fusion of the RPS6KA4 and CCDC88B genes. The fusion of the RPS6KA4 and CCDC88B genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS6KA4-CCDC88B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-RERE | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-REOR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-REGO | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-REGR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-OROR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GORE | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GROR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS6KA4-CCDC88B-20-AQAQ | 20 (40 μL) | 200 μL |
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RPS6KA4 Gene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Name: Ribosomal Protein S6 Kinase A4
Chromosome: CHR11: 64126624 -64139687
Locus: 11q13.1
CCDC88B Gene Summary
This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]
Gene Name: Coiled-coil Domain Containing 88B
Chromosome: CHR11: 64107689 -64125006
Locus: 11q13.1
Gene Diseases
The RPS6KA4 CCDC88B Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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