RPS6KA1-RASGRP3 Fusion FISH Probe
The RPS6KA1-RASGRP3 Fusion FISH Probe is used to confirm a fusion of the RPS6KA1 and RASGRP3 genes. The fusion of the RPS6KA1 and RASGRP3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS6KA1-RASGRP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-RERE | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-REOR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-REGO | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-REGR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-OROR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GORE | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GROR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS6KA1-RASGRP3-20-AQAQ | 20 (40 μL) | 200 μL |
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RPS6KA1 Gene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein S6 Kinase A1
Chromosome: CHR1: 26856248 -26901520
Locus: 1p36.11
RASGRP3 Gene Summary
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Gene Name: RAS Guanyl Releasing Protein 3
Chromosome: CHR2: 33661415 -33789798
Locus: 2p22.3
Gene Diseases
The RPS6KA1 RASGRP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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