RPS5-CALD1 Fusion FISH Probe
The RPS5-CALD1 Fusion FISH Probe is used to confirm a fusion of the RPS5 and CALD1 genes. The fusion of the RPS5 and CALD1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS5-CALD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-RERE | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-REOR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-REGO | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-REGR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-OROR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GORE | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GROR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS5-CALD1-20-AQAQ | 20 (40 μL) | 200 μL |
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CALD1 Gene Summary
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Caldesmon 1
Chromosome: CHR7: 134464163 -134655480
Locus: 7q33
RPS5 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein S5
Chromosome: CHR19: 58898635 -58906171
Locus: 19q13.43
Gene Diseases
The RPS5 CALD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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