RPS19-DMRTC2 Fusion FISH Probe
The RPS19-DMRTC2 Fusion FISH Probe is used to confirm a fusion of the RPS19 and DMRTC2 genes. The fusion of the RPS19 and DMRTC2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS19-DMRTC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-RERE | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-REOR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-REGO | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-REGR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-OROR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GORE | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GROR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS19-DMRTC2-20-AQAQ | 20 (40 μL) | 200 μL |
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RPS19 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein S19
Chromosome: CHR19: 42363987 -42375484
Locus: 19q13.2
DMRTC2 Gene Summary
The DMRT Like Family C2 (DMRTC2) gene is located on chr19 :42349085-42356397 at 19q13.2.
Gene Name: DMRT Like Family C2
Chromosome: CHR19: 42349085 -42356397
Locus: 19q13.2
Gene Diseases
The RPS19 DMRTC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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