RPS11-FLT3LG Fusion FISH Probe
The RPS11-FLT3LG Fusion FISH Probe is used to confirm a fusion of the RPS11 and FLT3LG genes. The fusion of the RPS11 and FLT3LG genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPS11-FLT3LG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-RERE | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-REOR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-REGO | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-REGR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-REAQ | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-ORRE | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-OROR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-ORGO | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GORE | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GOOR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GOGO | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GOGR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GRRE | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GROR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GRGO | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GRGR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-AQRE | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-AQOR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-AQGO | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-AQGR | 20 (40 μL) | 200 μL |
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| RPS11-FLT3LG-20-AQAQ | 20 (40 μL) | 200 μL |
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FLT3LG Gene Summary
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Gene Name: Fms Related Tyrosine Kinase 3 Ligand
Chromosome: CHR19: 49977465 -49989488
Locus: 19q13.33
RPS11 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
Gene Name: Ribosomal Protein S11
Chromosome: CHR19: 49999633 -50002944
Locus: 19q13.33
Gene Diseases
The RPS11 FLT3LG Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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