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RPP14-FLNB Fusion FISH Probe

The RPP14-FLNB Fusion FISH Probe is used to confirm a fusion of the RPP14 and FLNB genes. The fusion of the RPP14 and FLNB genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RPP14-FLNB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RPP14-FLNB-20-RERE 20 (40 μL) 200 μL
RPP14-FLNB-20-REOR 20 (40 μL) 200 μL
RPP14-FLNB-20-REGO 20 (40 μL) 200 μL
RPP14-FLNB-20-REGR 20 (40 μL) 200 μL
RPP14-FLNB-20-REAQ 20 (40 μL) 200 μL
RPP14-FLNB-20-ORRE 20 (40 μL) 200 μL
RPP14-FLNB-20-OROR 20 (40 μL) 200 μL
RPP14-FLNB-20-ORGO 20 (40 μL) 200 μL
RPP14-FLNB-20-ORAQ 20 (40 μL) 200 μL
RPP14-FLNB-20-GORE 20 (40 μL) 200 μL
RPP14-FLNB-20-GOOR 20 (40 μL) 200 μL
RPP14-FLNB-20-GOGO 20 (40 μL) 200 μL
RPP14-FLNB-20-GOGR 20 (40 μL) 200 μL
RPP14-FLNB-20-GOAQ 20 (40 μL) 200 μL
RPP14-FLNB-20-GRRE 20 (40 μL) 200 μL
RPP14-FLNB-20-GROR 20 (40 μL) 200 μL
RPP14-FLNB-20-GRGO 20 (40 μL) 200 μL
RPP14-FLNB-20-GRGR 20 (40 μL) 200 μL
RPP14-FLNB-20-GRAQ 20 (40 μL) 200 μL
RPP14-FLNB-20-AQRE 20 (40 μL) 200 μL
RPP14-FLNB-20-AQOR 20 (40 μL) 200 μL
RPP14-FLNB-20-AQGO 20 (40 μL) 200 μL
RPP14-FLNB-20-AQGR 20 (40 μL) 200 μL
RPP14-FLNB-20-AQAQ 20 (40 μL) 200 μL

FLNB Gene Summary

This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]

Gene Name: Filamin B

Chromosome: CHR3: 57994126 -58157982

Locus: 3p14.3

RPP14 Gene Summary

This gene encodes a subunit of ribonuclease P and has 3' to 5' exoribonuclease activity. Transcripts for this gene are bicistronic and include a conserved downstream open reading frame for the hydroxyacyl-thioester dehydratase type 2 (HTD2) gene. [provided by RefSeq, May 2017]

Gene Name: Ribonuclease P/MRP Subunit P14

Chromosome: CHR3: 58291971 -58305920

Locus: 3p14.3

Gene Diseases

The RPP14 FLNB Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.